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Developing a community-based genetic nomenclature for anole lizards

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dc.contributor.author Kusumi, Kenro en
dc.contributor.author Kulathinal, Rob J. en
dc.contributor.author Abzhanov, Arhat en
dc.contributor.author Boissinot, Stephane en
dc.contributor.author Crawford, Nicholas G. en
dc.contributor.author Faircloth, Brant C. en
dc.contributor.author Glenn, Travis C. en
dc.contributor.author Janes, Daniel E. en
dc.contributor.author Losos, Jonathan B. en
dc.contributor.author Menke, Douglas B. en
dc.contributor.author Poe, Steven en
dc.contributor.author Sanger, Thomas J. en
dc.contributor.author Schneider, Christopher J. en
dc.contributor.author Stapley, Jessica en
dc.contributor.author Wade, Juli en
dc.contributor.author Wilson-Rawls, Jeanne en
dc.date.accessioned 2013-12-03T13:56:49Z
dc.date.available 2013-12-03T13:56:49Z
dc.date.issued 2011
dc.identifier.citation Kusumi, Kenro, Kulathinal, Rob J., Abzhanov, Arhat, Boissinot, Stephane, Crawford, Nicholas G., Faircloth, Brant C., Glenn, Travis C., Janes, Daniel E., Losos, Jonathan B., Menke, Douglas B., Poe, Steven, Sanger, Thomas J., Schneider, Christopher J., Stapley, Jessica, Wade, Juli, and Wilson-Rawls, Jeanne. 2011. "<a href="https%3A%2F%2Frepository.si.edu%2Fhandle%2F10088%2F21687">Developing a community-based genetic nomenclature for anole lizards</a>." <em>BMC Genomics</em>. 12:554. <a href="https://doi.org/10.1186/1471-2164-12-554">https://doi.org/10.1186/1471-2164-12-554</a> en
dc.identifier.issn 1471-2164
dc.identifier.uri http://hdl.handle.net/10088/21687
dc.description.abstract Background: Comparative studies of amniotes have been hindered by a dearth of reptilian molecular sequences. With the genomic assembly of the green anole, Anolis carolinensis available, non-avian reptilian genes can now be compared to mammalian, avian, and amphibian homologs. Furthermore, with more than 350 extant species in the genus Anolis, anoles are an unparalleled example of tetrapod genetic diversity and divergence. As an important ecological, genetic and now genomic reference, it is imperative to develop a standardized Anolis gene nomenclature alongside associated vocabularies and other useful metrics. Results: Here we report the formation of the Anolis Gene Nomenclature Committee (AGNC) and propose a standardized evolutionary characterization code that will help researchers to define gene orthology and paralogy with tetrapod homologs, provide a system for naming novel genes in Anolis and other reptiles, furnish abbreviations to facilitate comparative studies among the Anolis species and related iguanid squamates, and classify the geographical origins of Anolis subpopulations. Conclusions: This report has been generated in close consultation with members of the Anolis and genomic research communities, and using public database resources including NCBI and Ensembl. Updates will continue to be regularly posted to new research community websites such as lizardbase. We anticipate that this standardized gene nomenclature will facilitate the accessibility of reptilian sequences for comparative studies among tetrapods and will further serve as a template for other communities in their sequencing and annotation initiatives. en
dc.relation.ispartof BMC Genomics en
dc.title Developing a community-based genetic nomenclature for anole lizards en
dc.type Journal Article en
dc.identifier.srbnumber 109650
dc.identifier.doi 10.1186/1471-2164-12-554
rft.jtitle BMC Genomics
rft.volume 12
rft.spage 554
dc.description.SIUnit Peer-Reviewed en
dc.description.SIUnit STRI en
dc.citation.spage 554

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