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First Complete Mitochondrial Genome Sequence from a Box Jellyfish Reveals a Highly Fragmented Linear Architecture and Insights into Telomere Evolution

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dc.contributor.author Smith, David Roy en
dc.contributor.author Kayal, Ehsan en
dc.contributor.author Yanagihara, Angel A. en
dc.contributor.author Collins, Allen Gilbert en
dc.contributor.author Pirro, Stacy en
dc.contributor.author Keeling, Patrick J. en
dc.date.accessioned 2013-09-27T12:27:32Z
dc.date.available 2013-09-27T12:27:32Z
dc.date.issued 2012
dc.identifier.citation Smith, David Roy, Kayal, Ehsan, Yanagihara, Angel A., Collins, Allen Gilbert, Pirro, Stacy, and Keeling, Patrick J. 2012. "<a href="https%3A%2F%2Frepository.si.edu%2Fhandle%2F10088%2F21458">First Complete Mitochondrial Genome Sequence from a Box Jellyfish Reveals a Highly Fragmented Linear Architecture and Insights into Telomere Evolution</a>." <em>Genome Biology and Evolution</em>. 4 (1):52&ndash;58. <a href="https://doi.org/10.1093/gbe/evr127">https://doi.org/10.1093/gbe/evr127</a> en
dc.identifier.issn 1759-6653
dc.identifier.uri http://hdl.handle.net/10088/21458
dc.description.abstract Animal mitochondrial DNAs (mtDNAs) are typically single circular chromosomes, with the exception of those from medusozoan cnidarians (jellyfish and hydroids), which are linear and sometimes fragmented. Most medusozoans have linear monomeric or linear bipartite mitochondrial genomes, but preliminary data have suggested that box jellyfish (cubozoans) have mtDNAs that consist of many linear chromosomes. Here, we present the complete mtDNA sequence from the winged box jellyfish Alatina moseri (the first from a cubozoan). This genome contains unprecedented levels of fragmentation: 18 unique genes distributed over eight 2.9- to 4.6-kb linear chromosomes. The telomeres are identical within and between chromosomes, and recombination between subtelomeric sequences has led to many genes initiating or terminating with sequences from other genes (the most extreme case being 150 nt of a ribosomal RNA containing the 5&#39; end of nad2), providing evidence for a gene conversion-based model of telomere evolution. The silent-site nucleotide variation within the A. moseri mtDNA is among the highest observed from a eukaryotic genome and may be associated with elevated rates of recombination. en
dc.relation.ispartof Genome Biology and Evolution en
dc.title First Complete Mitochondrial Genome Sequence from a Box Jellyfish Reveals a Highly Fragmented Linear Architecture and Insights into Telomere Evolution en
dc.type Journal Article en
dc.identifier.srbnumber 110806
dc.identifier.doi 10.1093/gbe/evr127
rft.jtitle Genome Biology and Evolution
rft.volume 4
rft.issue 1
rft.spage 52
rft.epage 58
dc.description.SIUnit NMNH en
dc.description.SIUnit NH-Invertebrate Zoology en
dc.description.SIUnit Peer-reviewed en
dc.citation.spage 52
dc.citation.epage 58


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