Browsing STRI Staff Publications by Author "Jakobs, Daniel"

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Fluorescence Correlation Spectroscopy in Drug Discovery: Study of Alexa532-Endothelin 1 Binding to the Endothelin ET<SUB>A</SUB> Receptor to Describe the Pharmacological Profile of Natural Products

Caballero-George, Catherina; Sorkalla, Thomas; Jakobs, Daniel; Bolanos, Jessica; Raja, Huzefa; Shearer, Carol; Bermingham, Eldredge; Haeberlein, Hanns (2012)

Fluorescence correlation spectroscopy and the newly synthesized Alexa532-ET1 were used to study the dynamics of the endothelin ETA receptor-ligand complex alone and under the influence of a semisynthetic selective antagonist ...

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