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Browsing by Author "Moore, Bradley S."

Browsing by Author "Moore, Bradley S."

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  • Biosynthesis of coral settlement cue tetrabromopyrrole in marine bacteria by a uniquely adapted brominase-thioesterase enzyme pair 
    Gamal, Abrahim El; Agarwal, Vinayak; Diethelm, Stefan; Rahman, Imran; Schorn, Michelle A.; Sneed, Jennifer M.; Louie, Gordon V.; Whalen, Kristen E.; Mincer, Tracy J.; Noel, Joseph P.; Paul, Valerie J.; Moore, Bradley S. (2016)
    Halogenated pyrroles (halopyrroles) are common chemical moieties found in bioactive bacterial natural products. The halopyrrole moieties of mono- and dihalopyrrole-containing compounds arise from a conserved mechanism in ...
  • Complexity of Naturally Produced Polybrominated Diphenyl Ethers Revealed via Mass Spectrometry 
    Agarwal, Vinayak; Li, Jie; Rahman, Imran; Borgen, Miles; Aluwihare, Lihini I.; Biggs, Jason S.; Paul, Valerie J.; Moore, Bradley S. (2015)
  • Coral settlement induction by tetrabromopyrrole is widespread among Caribbean corals and compound specific 
    Sneed, Jennifer M.; Demko, Alyssa M.; Miller, Margaret W.; Yi, Dongqi; Moore, Bradley S.; Agarwal, Vinayak; Paul, Valerie J. (2024)
    Tetrabromopyrrole (TBP) is a readily biosynthesized marine proteobacterial compound that induces coral settlement (attachment and metamorphosis) at concentrations ranging from 50 – 250 ng ml -1 (0.13 – 0.65 µM). This ...
  • Metagenomic discovery of polybrominated diphenyl ether biosynthesis by marine sponges 
    Agarwal, Vinayak; Blanton, Jessica M.; Podell, Sheila; Taton, Arnaud; Schorn, Michelle A.; Busch, Julia; Lin, Zhenjian; Schmidt, Eric W.; Jensen, Paul R.; Paul, Valerie J.; Biggs, Jason S.; Golden, James W.; Allen, Eric E.; Moore, Bradley S. (2017)
  • The Natural Product Domain Seeker version 2 (NaPDoS2) webtool relates ketosynthase phylogeny to biosynthetic function 
    Klau, Leesa J.; Podell, Sheila; Creamer, Kaitlin E.; Demko, Alyssa M.; Singh, Hans W.; Allen, Eric E.; Moore, Bradley S.; Ziemert, Nadine; Letzel, Anne Catrin; Jensen, Paul R. (2022)
    The Natural Product Domain Seeker (NaPDoS) webtool detects and classifies ketosynthase (KS) and condensation domains from genomic, metagenomic, and amplicon sequence data. Unlike other tools, a phylogeny-based clas-sification ...
  • Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking 
    Wang, Mingxun; Carver, Jeremy J.; Phelan, Vanessa V.; Sanchez, Laura M.; Garg, Neha; Peng, Yao; Nguyen, Don Duy; Watrous, Jeramie; Kapono, Clifford A.; Luzzatto-Knaan, Tal; Porto, Carla; Bouslimani, Amina; Melnik, Alexey V.; Meehan, Michael J.; Liu, Wei-Ting; Crüsemann, Max; Boudreau, Paul D.; Esquenazi, Eduardo; Sandoval-Calderón, Mario; Kersten, Roland D.; Pace, Laura A.; Quinn, Robert A.; Duncan, Katherine R.; Hsu, Cheng-Chih; Floros, Dimitrios J.; Gavilan, Ronnie G.; Kleigrewe, Karin; Northen, Trent; Dutton, Rachel J.; Parrot, Delphine; Carlson, Erin E.; Aigle, Bertrand; Michelsen, Charlotte F.; Jelsbak, Lars; Sohlenkamp, Christian; Pevzner, Pavel; Edlund, Anna; McLean, Jeffrey; Piel, Jö; Murphy, Brian T.; Gerwick, Lena; Liaw, Chih-Chuang; Yang, Yu-Liang; Humpf, Hans-Ulrich; Maansson, Maria; Keyzers, Robert A.; Sims, Amy C.; Johnson, Andrew R.; Sidebottom, Ashley M.; Sedio, Brian E.; Klitgaard, Andreas; Larson, Charles B.; Cristopher, Boya P.,; Torres-Mendoza, Daniel; Gonzalez, David J.; Silva, Denise B.; Marques, Lucas M.; Demarque, Daniel P.; Pociute, Egle; O'Neill, Ellis C.; Briand, Enora; Helfrich, Eric J. N.; Granatosky, Eve A.; Glukhov, Evgenia; Ryffel, Florian; Houson, Hailey; Mohimani, Hosein; Kharbush, Jenan J.; Zeng, Yi; Vorholt, Julia A.; Kurita, Kenji L.; Charusanti, Pep; McPhail, Kerry L.; Nielsen, Kristian Fog; Vuong, Lisa; Elfeki, Maryam; Traxler, Matthew F.; Engene, Niclas; Koyama, Nobuhiro; Vining, Oliver B.; Baric, Ralph; Silva, Ricardo R.; Mascuch, Samantha J.; Tomasi, Sophie; Jenkins, Stefan; Macherla, Venkat; Hoffman, Thomas; Agarwal, Vinayak; Williams, Philip G.; Dai, Jingqui; Neupane, Ram; Gurr, Joshua; Rodríguez, Andrés M. C.; Lamsa, Anne; Zhang, Chen; Dorrestein, Kathleen; Duggan, Brendan M.; Almaliti, Jehad; Allard, Pierre-Marie; Phapale, Prasad; Nothias, Louis-Felix; Alexandrov, Theodore; Litaudon, Marc; Wolfender, Jean-Luc; Kyle, Jennifer E.; Metz, Thomas O.; Peryea, Tyler; Nguyen, Dac-Trung; VanLeer, Danielle; Shinn, Paul; Jadhav, Ajit; Müller, Rolf; Waters, Katrina M.; Shi, Wenyuan; Liu, Xueting; Zhang, Lixin; Knight, Rob; Jensen, Paul R.; Palsson, Bernhard Ø.; Pogliano, Kit; Linington, Roger G.; Gutiérrez, Marcelino; Lopes, Norberto P.; Gerwick, William H.; Moore, Bradley S.; Dorrestein, Pieter C.; Bandeira, Nuno (2016)
    The potential of the diverse chemistries present in natural products (NP) for biotechnology and medicine remains untapped because NP databases are not searchable with raw data and the NP community has no way to share data ...

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