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Browsing by Author "Lindblad-Toh, Kerstin"

Browsing by Author "Lindblad-Toh, Kerstin"

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  • Aquatic adaptation and depleted diversity: a deep dive into the genomes of the sea otter and giant otter 
    Beichman, Annabel C.; Koepfli, Klaus-Peter; Li, Gang; Murphy, William; Dobrynin, Pasha; Kilver, Sergei; Tinker, M. T.; Murray, Michael J.; Johnson, Jeremy; Lindblad-Toh, Kerstin; Karlsson, Elinor K.; Lohmueller, Kirk E.; Wayne, Robert K. (2019)
    Despite its recent invasion into the marine realm, the sea otter (Enhydra lutris) has evolved a suite of adaptations for life in cold coastal waters, including limb modifications and dense insulating fur. This uniquely ...
  • Broad Host Range of SARS-CoV-2 Predicted by Comparative and Structural Analysis of ACE2 in Vertebrates 
    Damas, Joana; Hughes, Graham M.; Keough, Kathleen C.; Painter, Corrie A.; Persky, Nicole S.; Corbo, Marco; Hiller, Michael; Koepfli, Klaus-Peter; Pfenning, Andreas R.; Zhao, Huabin; Genereux, Diane P.; Swofford, Ross; Pollard, Katherine S.; Ryder, Oliver A.; Nweeia, Martin T.; Lindblad-Toh, Kerstin; Teeling, Emma C.; Karlsson, Elinor K.; Lewin, Harris A. (2020)
    Abstract The novel coronavirus SARS-CoV-2 is the cause of Coronavirus Disease-2019 (COVID-19). The main receptor of SARS-CoV-2, angiotensin I converting enzyme 2 (ACE2), is now undergoing extensive scrutiny to understand ...
  • The contribution of historical processes to contemporary extinction risk in placental mammals 
    Wilder, Aryn P.; Supple, Megan A.; Subramanian, Ayshwarya; Mudide, Anish; Swofford, Ross; Serres-Armero, Aitor; Steiner, Cynthia; Koepfli, Klaus-Peter; Genereux, Diane P.; Karlsson, Elinor K.; Lindblad-Toh, Kerstin; Marques-Bonet, Tomas; Munoz Fuentes, Violeta; Foley, Kathleen; Meyer, Wynn K.; Zoonomia Consortium‡; Ryder, Oliver A.; Shapiro, Beth; Andrews, Gregory; Armstrong, Joel C.; Bianchi, Matteo; Birren, Bruce W.; Bredemeyer, Kevin R.; Breit, Ana M.; Christmas, Matthew J.; Clawson, Hiram; Damas, Joana; Di Palma, Federica; Diekhans, Mark; Dong, Michael X.; Eizirik, Eduardo; Fan, Kaili; Fanter, Cornelia; Foley, Nicole M.; Forsberg-Nilsson, Karin; Garcia, Carlos J.; Gatesy, John; Gazal, Steven; Genereux, Diane P.; Goodman, Linda; Grimshaw, Jenna; Halsey, Michaela K.; Harris, Andrew J.; Hickey, Glenn; Hiller, Michael; Hindle, Allyson G.; Hubley, Robert M.; Hughes, Graham M.; Johnson, Jeremy; Juan, David; Kaplow, Irene M.; Karlsson, Elinor K.; Keough, Kathleen C.; Kirilenko, Bogdan; Koepfli, Klaus-Peter; Korstian, Jennifer M.; Kowalczyk, Amanda; Kozyrev, Sergey V.; Lawler, Alyssa J.; Lawless, Colleen; Lehmann, Thomas; Levesque, Danielle L.; Lewin, Harris A.; Li, Xue; Lind, Abigail; Lindblad-Toh, Kerstin; Mackay-Smith, Ava; Marinescu, Voichita D.; Marques-Bonet, Tomas; Mason, Victor C.; Meadows, Jennifer R. S.; Meyer, Wynn K.; Moore, Jill E.; Moreira, Lucas R.; Moreno-Santillan, Diana; Morrill, Kathleen M.; Muntané, Gerard; Murphy, William J.; Navarro, Arcadi; Nweeia, Martin; Ortmann, Sylvia; Osmanski, Austin; Paten, Benedict; Paulat, Nicole S.; Pfenning, Andreas R.; Phan, BaDoi N.; Pollard, Katherine S.; Pratt, Henry E.; Ray, David A.; Reilly, Steven K.; Rosen, Jeb R.; Ruf, Irina; Ryan, Louise; Ryder, Oliver A.; Sabeti, Pardis C.; Schäffer, Daniel E.; Serres, Aitor; Shapiro, Beth; Smit, Arian F. A.; Springer, Mark; Srinivasan, Chaitanya; Steiner, Cynthia; Storer, Jessica M.; Sullivan, Kevin A. M.; Sullivan, Patrick F.; Sundström, Elisabeth; Supple, Megan A.; Swofford, Ross; Talbot, Joy-El; Teeling, Emma; Turner-Maier, Jason; Valenzuela, Alejandro; Wagner, Franziska; Wallerman, Ola; Wang, Chao; Wang, Juehan; Weng, Zhiping; Wilder, Aryn P.; Wirthlin, Morgan E.; Xue, James R.; Zhang, Xiaomeng (2023)
    Species persistence can be influenced by the amount, type, and distribution of diversity across the genome, suggesting a potential relationship between historical demography and resilience. In this study, we surveyed genetic ...
  • The Earth BioGenome Project 2020: Starting the clock 
    Lewin, Harris A.; Richards, Stephen; Lieberman Aiden, Erez; Allende, Miguel L.; Archibald, John M.; Bálint, Miklós; Barker, Katharine B.; Baumgartner, Bridget; Belov, Katherine; Bertorelle, Giorgio; Blaxter, Mark L.; Cai, Jing; Caperello, Nicolette D.; Carlson, Keith; Castilla-Rubio, Juan; Chaw, Shu-Miaw; Chen, Lei; Childers, Anna K.; Coddington, Jonathan A.; Conde, Dalia A.; Corominas, Montserrat; Crandall, Keith A.; Crawford, Andrew J.; DiPalma, Federica; Durbin, Richard; Ebenezer, ThankGod E.; Edwards, Scott V.; Fedrigo, Olivier; Flicek, Paul; Formenti, Giulio; Gibbs, Richard A.; Gilbert, M. T.; Goldstein, Melissa M.; Graves, Jennifer Marshall; Greely, Henry T.; Grigoriev, Igor V.; Hackett, Kevin J.; Hall, Neil; Haussler, David; Helgen, Kristofer M.; Hogg, Carolyn J.; Isobe, Sachiko; Jakobsen, Kjetill Sigurd; Janke, Axel; Jarvis, Erich D.; Johnson, Warren E.; Jones, Steven J. M.; Karlsson, Elinor K.; Kersey, Paul J.; Kim, Jin-Hyoung; Kress, W. John; Kuraku, Shigehiro; Lawniczak, Mara K. N.; Leebens-Mack, James; Li, Xueyan; Lindblad-Toh, Kerstin; Liu, Xin; Lopez, Jose V.; Marques-Bonet, Tomas; Mazard, Sophie; Mazet, Jonna A. K.; Mazzoni, Camila J.; Myers, Eugene W.; O'Neill, Rachel J.; Paez, Sadye; Park, Hyun; Robinson, Gene E.; Roquet, Cristina; Ryder, Oliver A.; Sabir, Jamal S. M.; Shaffer, H. B.; Shank, Timothy M.; Sherkow, Jacob S.; Soltis, Pamela S.; Tang, Boping; Tedersoo, Leho; Uliano-Silva, Marcela; Wang, Kun; Wei, Xiaofeng; Wetzer, Regina; Wilson, Julia L.; Xu, Xun; Yang, Huanming; Yoder, Anne D.; Zhang, Guojie (2022)
  • Evolution of the ancestral mammalian karyotype and syntenic regions 
    Damas, Joana; Corbo, Marco; Kim, Jaebum; Turner-Maier, Jason; Farré, Marta; Larkin, Denis M.; Ryder, Oliver A.; Steiner, Cynthia; Houck, Marlys L.; Hall, Shaune; Shiue, Lily; Thomas, Stephen; Swale, Thomas; Daly, Mark; Korlach, Jonas; Uliano-Silva, Marcela; Mazzoni, Camila J.; Birren, Bruce W.; Genereux, Diane P.; Johnson, Jeremy; Lindblad-Toh, Kerstin; Karlsson, Elinor K.; Nweeia, Martin T.; Johnson, Rebecca N.; Consortium, Zoonomia; Lewin, Harris A.; Andrews, Gregory; Armstrong, Joel C.; Bianchi, Matteo; Birren, Bruce W.; Bredemeyer, Kevin R.; Breit, Ana M.; Christmas, Matthew J.; Clawson, Hiram; Damas, Joana; Palma, Federica Di; Diekhans, Mark; Dong, Michael X.; Eizirik, Eduardo; Fan, Kaili; Fanter, Cornelia; Foley, Nicole M.; Forsberg-Nilsson, Karin; Garcia, Carlos J.; Gatesy, John; Gazal, Steven; Genereux, Diane P.; Goodman, Linda; Grimshaw, Jenna; Halsey, Michaela K.; Harris, Andrew J.; Hickey, Glenn; Hiller, Michael; Hindle, Allyson G.; Hubley, Robert M.; Hughes, Graham M.; Johnson, Jeremy; Juan, David; Kaplow, Irene M.; Karlsson, Elinor K.; Keough, Kathleen C.; Kirilenko, Bogdan; Koepfli, Klaus-Peter; Korstian, Jennifer M.; Kowalczyk, Amanda; Kozyrev, Sergey V.; Lawler, Alyssa J.; Lawless, Colleen; Lehmann, Thomas; Levesque, Danielle L.; Lewin, Harris A.; Li, Xue; Lind, Abigail; Lindblad-Toh, Kerstin; Mackay-Smith, Ava; Marinescu, Voichita D.; Marques-Bonet, Tomas; Mason, Victor C.; Meadows, Jennifer R. S.; Meyer, Wynn K.; Moore, Jill E.; Moreira, Lucas R.; Moreno-Santillan, Diana; Morrill, Kathleen M.; Muntané, Gerard; Murphy, William J.; Navarro, Arcadi; Nweeia, Martin; Ortmann, Sylvia; Osmanski, Austin; Paten, Benedict; Paulat, Nicole S.; Pfenning, Andreas R.; Phan, BaDoi N.; Pollard, Katherine S.; Pratt, Henry E.; Ray, David A.; Reilly, Steven K.; Rosen, Jeb R.; Ruf, Irina; Ryan, Louise; Ryder, Oliver A.; Sabeti, Pardis C.; Schäffer, Daniel E.; Serres, Aitor; Shapiro, Beth; Smit, Arian F. A.; Springer, Mark; Srinivasan, Chaitanya; Steiner, Cynthia; Storer, Jessica M.; Sullivan, Kevin A. M.; Sullivan, Patrick F.; Sundström, Elisabeth; Supple, Megan A.; Swofford, Ross; Talbot, Joy-El; Teeling, Emma; Turner-Maier, Jason; Valenzuela, Alejandro; Wagner, Franziska; Wallerman, Ola; Wang, Chao; Wang, Juehan; Weng, Zhiping; Wilder, Aryn P.; Wirthlin, Morgan E.; Xue, James R.; Zhang, Xiaomeng (2022)
    Decrypting the rearrangements that drive mammalian chromosome evolution is critical to understanding the molecular bases of speciation, adaptation, and disease susceptibility. Using 8 scaffolded and 26 chromosome-scale ...
  • Evolutionary constraint and innovation across hundreds of placental mammals 
    Christmas, Matthew J.; Kaplow, Irene M.; Genereux, Diane P.; Dong, Michael X.; Hughes, Graham M.; Li, Xue; Sullivan, Patrick F.; Hindle, Allyson G.; Andrews, Gregory; Armstrong, Joel C.; Bianchi, Matteo; Breit, Ana M.; Diekhans, Mark; Fanter, Cornelia; Foley, Nicole M.; Goodman, Daniel B.; Goodman, Linda; Keough, Kathleen C.; Kirilenko, Bogdan; Kowalczyk, Amanda; Lawless, Colleen; Lind, Abigail L.; Meadows, Jennifer R. S.; Moreira, Lucas R.; Redlich, Ruby W.; Ryan, Louise; Swofford, Ross; Valenzuela, Alejandro; Wagner, Franziska; Wallerman, Ola; Brown, Ashley R.; Damas, Joana; Fan, Kaili; Gatesy, John; Grimshaw, Jenna; Johnson, Jeremy; Kozyrev, Sergey V.; Lawler, Alyssa J.; Marinescu, Voichita D.; Morrill, Kathleen M.; Osmanski, Austin; Paulat, Nicole S.; Phan, BaDoi N.; Reilly, Steven K.; Schäffer, Daniel E.; Steiner, Cynthia; Supple, Megan A.; Wilder, Aryn P.; Wirthlin, Morgan E.; Xue, James R.; Zoonomia Consortium§; Birren, Bruce W.; Gazal, Steven; Hubley, Robert M.; Koepfli, Klaus-Peter; Marques-Bonet, Tomas; Meyer, Wynn K.; Nweeia, Martin; Sabeti, Pardis C.; Shapiro, Beth; Smit, Arian F. A.; Springer, Mark S.; Teeling, Emma C.; Weng, Zhiping; Hiller, Michael; Levesque, Danielle L.; Lewin, Harris A.; Murphy, William J.; Navarro, Arcadi; Paten, Benedict; Pollard, Katherine S.; Ray, David A.; Ruf, Irina; Ryder, Oliver A.; Pfenning, Andreas R.; Lindblad-Toh, Kerstin; Karlsson, Elinor K.; Andrews, Gregory; Armstrong, Joel C.; Bianchi, Matteo; Birren, Bruce W.; Bredemeyer, Kevin R.; Breit, Ana M.; Christmas, Matthew J.; Clawson, Hiram; Damas, Joana; Di Palma, Federica; Diekhans, Mark; Dong, Michael X.; Eizirik, Eduardo; Fan, Kaili; Fanter, Cornelia; Foley, Nicole M.; Forsberg-Nilsson, Karin; Garcia, Carlos J.; Gatesy, John; Gazal, Steven; Genereux, Diane P.; Goodman, Linda; Grimshaw, Jenna; Halsey, Michaela K.; Harris, Andrew J.; Hickey, Glenn; Hiller, Michael; Hindle, Allyson G.; Hubley, Robert M.; Hughes, Graham M.; Johnson, Jeremy; Juan, David; Kaplow, Irene M.; Karlsson, Elinor K.; Keough, Kathleen C.; Kirilenko, Bogdan; Koepfli, Klaus-Peter; Korstian, Jennifer M.; Kowalczyk, Amanda; Kozyrev, Sergey V.; Lawler, Alyssa J.; Lawless, Colleen; Lehmann, Thomas; Levesque, Danielle L.; Lewin, Harris A.; Li, Xue; Lind, Abigail; Lindblad-Toh, Kerstin; Mackay-Smith, Ava; Marinescu, Voichita D.; Marques-Bonet, Tomas; Mason, Victor C.; Meadows, Jennifer R. S.; Meyer, Wynn K.; Moore, Jill E.; Moreira, Lucas R.; Moreno-Santillan, Diana; Morrill, Kathleen M.; Muntané, Gerard; Murphy, William J.; Navarro, Arcadi; Nweeia, Martin; Ortmann, Sylvia; Osmanski, Austin; Paten, Benedict; Paulat, Nicole S.; Pfenning, Andreas R.; Phan, BaDoi N.; Pollard, Katherine S.; Pratt, Henry E.; Ray, David A.; Reilly, Steven K.; Rosen, Jeb R.; Ruf, Irina; Ryan, Louise; Ryder, Oliver A.; Sabeti, Pardis C.; Schäffer, Daniel E.; Serres, Aitor; Shapiro, Beth; Smit, Arian F. A.; Springer, Mark; Srinivasan, Chaitanya; Steiner, Cynthia; Storer, Jessica M.; Sullivan, Kevin A. M.; Sullivan, Patrick F.; Sundström, Elisabeth; Supple, Megan A.; Swofford, Ross; Talbot, Joy-El; Teeling, Emma; Turner-Maier, Jason; Valenzuela, Alejandro; Wagner, Franziska; Wallerman, Ola; Wang, Chao; Wang, Juehan; Weng, Zhiping; Wilder, Aryn P.; Wirthlin, Morgan E.; Xue, James R.; Zhang, Xiaomeng (2023)
    Zoonomia is the largest comparative genomics resource for mammals produced to date. By aligning genomes for 240 species, we identify bases that, when mutated, are likely to affect fitness and alter disease risk. At least ...
  • The genome of the green anole lizard and a comparative analysis with birds and mammals 
    Alföldi, Jessica; Di Palma, Frederica; Grabherr, Manfred; Williams, Christina; Kong, Lesheng; Mauceli, Evan; Russell, Pamela; Lowe, Craig B.; Glor, Richard E.; Jaffe, Jacob D.; Ray, David A.; Boissinot, Stephane; Shedlock, Andrew M.; Botka, Christopher; Castoe, Todd A.; Colbourne, John K.; Fujita, Matthew K.; Moreno, Ricardo Godinez; Boudewijn, F. Ten Hallers; Haussler, David; Heger, Andreas; Heiman, David; Janes, Daniel E.; Johnson, Jeremy; de Jong, Pieter J.; Koriabine, Maxim Y.; Lara, Marcia; Novick, Peter A.; Organ, Chris L.; Peach, Sally E.; Poe, Steven; Pollock, David D.; de Queiroz, Kevin; Sanger, Thomas; Searle, Steve; Smith, Jeremy D.; Smith, Zachary; Swofford, Ross; Turner-Maier, Jason; Wade, Juli; Young, Sarah; Zadissa, Amonida; Edwards, Scott V.; Glenn, Travis C.; Schneider, Christopher J.; Losos, Jonathan B.; Lander, Eric S.; Breen, Matthew; Ponting, Chris P.; Lindblad-Toh, Kerstin (2011)
  • Standards recommendations for the Earth BioGenome Project 
    Lawniczak, Mara K. N.; Durbin, Richard; Flicek, Paul; Lindblad-Toh, Kerstin; Wei, Xiaofeng; Archibald, John M.; Baker, William J.; Belov, Katherine; Blaxter, Mark L.; Bonet, Tomas Marques; Childers, Anna K.; Coddington, Jonathan A.; Crandall, Keith A.; Crawford, Andrew J.; Davey, Robert P.; Di Palma, Federica; Fang, Qi; Haerty, Wilfried; Hall, Neil; Hoff, Katharina J.; Howe, Kerstin; Jarvis, Erich D.; Johnson, Warren E.; Johnson, Rebecca N.; Kersey, Paul J.; Liu, Xin; Lopez, Jose Victor; Myers, Eugene W.; Pettersson, Olga Vinnere; Phillippy, Adam M.; Poelchau, Monica F.; Pruitt, Kim D.; Rhie, Arang; Castilla-Rubio, Juan Carlos; Sahu, Sunil Kumar; Salmon, Nicholas A.; Soltis, Pamela S.; Swarbreck, David; Thibaud-Nissen, Francoise; Wang, Sibo; Wegrzyn, Jill L.; Zhang, Guojie; Zhang, He; Lewin, Harris A.; Richards, Stephen (2022)
    A global international initiative, such as the Earth BioGenome Project (EBP), requires both agreement and coordination on standards to ensure that the collective effort generates rapid progress toward its goals. To this ...
  • Why sequence all eukaryotes? 
    Blaxter, Mark; Archibald, John M.; Childers, Anna K.; Coddington, Jonathan A.; Crandall, Keith A.; Di Palma, Federica; Durbin, Richard; Edwards, Scott V.; Graves, Jennifer A. M.; Hackett, Kevin J.; Hall, Neil; Jarvis, Erich D.; Johnson, Rebecca N.; Karlsson, Elinor K.; Kress, W. John; Kuraku, Shigehiro; Lawniczak, Mara K. N.; Lindblad-Toh, Kerstin; Lopez, Jose V.; Moran, Nancy A.; Robinson, Gene E.; Ryder, Oliver A.; Shapiro, Beth; Soltis, Pamela S.; Warnow, Tandy; Zhang, Guojie; Lewin, Harris A. (2022)
    Life on Earth has evolved from initial simplicity to the astounding complexity we experience today. Bacteria and archaea have largely excelled in metabolic diversification, but eukaryotes additionally display abundant ...

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