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Browsing by Author "Drexler, Jan Felix"

Browsing by Author "Drexler, Jan Felix"

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  • Bats carry pathogenic hepadnaviruses antigenically related to hepatitis B virus and capable of infecting human hepatocytes 
    Drexler, Jan Felix; Geipel, Andreas; König, Alexander; Corman, Victor M.; Riel, Debby van; Leijten, Lonneke M.; Bremer, Corinna M.; Rasche, Andrea; Cottontail, Veronika M.; Maganga, Gael D.; Schlegel, Mathias; Müller, Marcel A.; Adam, Alexander; Klose, Stefan M.; Carneiro, Aroldo José Borges; Stöcker, Andreas; Franke, Carlos Roberto; Gloza-Rausch, Florian; Geyer, Joachim; Annan, Augustina; Adu-Sarkodie, Yaw; Oppong, Samuel; Binger, Tabea; Vallo, Peter; Tschapka, Marco; Ulrich, Rainer G.; Gerlich, Wolfram H.; Leroy, Eric; Kuiken, Thijs; Glebe, Dieter; Drosten, Christian (2013)
    The hepatitis B virus (HBV), family Hepadnaviridae, is one of most relevant human pathogens. HBV origins are enigmatic, and no zoonotic reservoirs are known. Here, we screened 3,080 specimens from 54 bat species representing ...
  • Bats host major mammalian paramyxoviruses 
    Drexler, Jan Felix; Corman, Victor Max; Mueller, Marcel Alexander; Maganga, Gael Darren; Vallo, Peter; Binger, Tabea; Gloza-Rausch, Florian; Rasche, Andrea; Yordanov, Stoian; Seebens, Antje; Oppong, Samuel; Sarkodie, Yaw Adu; Pongombo, Celestin; Lukashev, Alexander N.; Schmidt-Chanasit, Jonas; Stoecker, Andreas; Borges Carneiro, Aroldo Jose; Erbar, Stephanie; Maisner, Andrea; Fronhoffs, Florian; Buettner, Reinhard; Kalko, Elisabeth Klara Viktoria; Kruppa, Thomas; Franke, Carlos Roberto; Kallies, Rene; Yandoko, Emmanuel R. N.; Herrler, Georg; Reusken, Chantal; Hassanin, Alexandre; Krueger, Detlev H.; Matthee, Sonja; Ulrich, Rainer G.; Leroy, Eric M.; Drosten, Christian (2012)
    The large virus family Paramyxoviridae includes some of the most significant human and livestock viruses, such as measles-, distemper-, mumps-, parainfluenza-, Newcastle disease-, respiratory syncytial virus and ...
  • Bats worldwide carry hepatitis E-related viruses that form a putative novel genus within the family Hepeviridae 
    Drexler, Jan Felix; Seelen, Annika; Corman, Victor Max; Tateno, Adriana Fumie; Cottontail, Veronika; Zerbinati, Rodrigo Melim; Gloza-Rausch, Florian; Klose, Stefan M.; Adu-Sarkodie, Yaw; Oppong, Samuel K.; Kalko, Elisabeth Klara Viktoria; Osterman, Andreas; Rasche, Andrea; Adam, Alexander; Muller, Marcel A.; Ulrich, Rainer G.; Leroy, Eric M.; Lukashev, Alexander N.; Drosten, Christian (2012)
  • Evidence for an ancestral association of human coronavirus 229E with bats 
    Corman, Victor Max; Baldwin, Heather J.; Fumie Tateno, Adriana; Melim Zerbinati, Rodrigo; Annan, Augustina; Owusu, Michael; Nkrumah, Evans Ewald; Maganga, Gael Darren; Oppong, Samuel; Adu-Sarkodie, Yaw; Vallo, Peter; da Silva Filho, Luiz Vicente Ribeiro Ferreira; Leroy, Eric M.; Thiel, Volker; van der Hoek, Lisa; Poon, Leo L. M.; Tschapka, Marco; Drosten, Christian; Drexler, Jan Felix (2015)
    We previously showed that close relatives of human coronavirus (HCoV)-229E exist in African bats. The small sample and limited genomic characterizations prevented further analyses so far. Here, we tested 2,087 fecal specimens ...
  • Evidence for widespread infection of African bats with Crimean-Congo hemorrhagic fever-like viruses 
    Müller, Marcel A.; Devignot, Stéphanie; Lattwein, Erik; Corman, Victor Max; Maganga, Gaël D.; Gloza-Rausch, Florian; Binger, Tabea; Vallo, Peter; Emmerich, Petra; Cottontail, Veronika M.; Tschapka, Marco; Oppong, Samuel; Drexler, Jan Felix; Weber, Friedemann; Leroy, Eric M.; Drosten, Christian (2016)
    Crimean Congo hemorrhagic fever virus (CCHFV) is a highly virulent tick-borne pathogen that causes hemorrhagic fever in humans. The geographic range of human CCHF cases largely reflects the presence of ticks. However, ...
  • Henipavirus RNA in African bats 
    Drexler, Jan Felix; Corman, Victor Max; Gloza-Rausch, Florian; Seebens, Antje; Annan, Augustina; Ipsen, Anne; Kruppa, Thomas; Mueller, Marcel A.; Kalko, Elisabeth Klara Viktoria; Adu-Sarkodie, Yaw; Oppong, Samuel; Drosten, Christian (2009)
    Henipaviruses (Hendra and Nipah virus) are highly pathogenic members of the family Paramyxoviridae. Fruit-eating bats of the Pteropus genus have been suggested as their natural reservoir. Human Henipavirus infections have ...
  • Host Biology and Anthropogenic Factors Affect Hepadnavirus Infection in a Neotropical Bat 
    Hiller, Thomas; Rasche, Andrea; Brändel, Stefan Dominik; König, Alexander; Jeworowski, Lara; O'Mara, Teague M.; Cottontail, Veronika; Page, Rachel A.; Glebe, Dieter; Drexler, Jan Felix; Tschapka, Marco (2019)
    The tent-making bat hepatitis B virus (TBHBV) is a hepadnavirus closely related to human hepatitis B virus. The ecology of TBHBV is unclear. We show that it is widespread and highly diversified in Peters' tent-making bats ...
  • Human Betacoronavirus 2c EMC/2012-related viruses in bats, Ghana and Europe 
    Annan, Augustina; Baldwin, Heather J.; Corman, Victor Max; Klose, Stefan M.; Owusu, Michael; Nkrumah, Evans Ewald; Badu, Ebenezer Kofi; Anti, Priscilla; Agbenyega, Olivia; Oppong, Samuel; Sarkodie, Yaw Adu; Kalko, Elisabeth K. V.; Lina, Peter H. C.; Godlevska, Elena V.; Reusken, Chantal; Seebens, Antje; Gloza-Rausch, Florian; Vallo, Peter; Tschapka, Marco; Drosten, Christian; Drexler, Jan Felix (2013)
  • Mammalian deltavirus without hepadnavirus coinfection in the neotropical rodent <I>Proechimys semispinosus</I> 
    Paraskevopoulou, Sofia; Pirzer, Fabian; Goldmann, Nora; Schmid, Julian; Corman, Victor Max; Gottula, Lina Theresa; Schroeder, Simon; Rasche, Andrea; Muth, Doreen; Drexler, Jan Felix; Heni, Alexander Christoph; Eibner, Georg Joachim; Page, Rachel A.; Jones, Terry C.; Müller, Marcel A.; Sommer, Simone; Glebe, Dieter; Drosten, Christian (2020)
    Hepatitis delta virus (HDV) is a human hepatitis-causing RNA virus, unrelated to any other taxonomic group of RNA viruses. Its occurrence as a satellite virus of hepatitis B virus (HBV) is a singular case in animal virology ...
  • Serological evidence of influenza A viruses in frugivorous bats from Africa 
    Freidl, Gudrun Stephanie; Binger, Tabea; Müller, Marcel Alexander; de Bruin, Erwin; van Beek, Janko; Corman, Victor Max; Rasche, Andrea; Drexler, Jan Felix; Sylverken, Augustina; Oppong, Samuel K.; Adu-Sarkodie, Yaw; Tschapka, Marco; Cottontail, Veronika M.; Drosten, Christian; Koopmans, Marion (2015)
    Bats are likely natural hosts for a range of zoonotic viruses such as Marburg, Ebola, Rabies, as well as for various Corona- and Paramyxoviruses. In 2009/10, researchers discovered RNA of two novel influenza virus subtypes ...
  • Two Novel Parvoviruses in Frugivorous New and Old World Bats 
    Canuti, Marta; Eis-Huebinger, Anna Maria; Deijs, Martin; de Vries, Michel; Drexler, Jan Felix; Oppong, Samuel K.; Mueller, Marcel A.; Klose, Stefan M.; Wellinghausen, Nele; Cottontail, Veronika M.; Kalko, Elisabeth Klara Viktoria; Drosten, Christian; van der Hoek, Lia (2011)
    Bats, a globally distributed group of mammals with high ecological importance, are increasingly recognized as natural reservoir hosts for viral agents of significance to human and animal health. In the present study, we ...
  • Type I Interferon Reaction to Viral Infection in Interferon-Competent, Immortalized Cell Lines from the African Fruit Bat Eidolon helvum 
    Biesold, Susanne E.; Ritz, Daniel; Gloza-Rausch, Florian; Wollny, Robert; Drexler, Jan Felix; Corman, Victor M.; Kalko, Elisabeth Klara Viktoria; Oppong, Samuel; Drosten, Christian; Mueller, Marcel A. (2011)
    Bats harbor several highly pathogenic zoonotic viruses including Rabies, Marburg, and henipaviruses, without overt clinical symptoms in the animals. It has been suspected that bats might have evolved particularly effective ...

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