Novel lactone chamigrene-derived metabolites from <I>Laurencia majuscula</I>

Diaz Marrero, Ara R.; Brito, Inmaculada; de la Rosa, Jose M.; D'Croz, Luis; Fabeo, Oscar; Ruiz-Perez, Catalina; Darias, Jose; Cueto, Mercedes

Novel lactone chamigrene-derived metabolites from Laurencia majuscula

Diaz Marrero, Ara R.;Brito, Inmaculada;de la Rosa, Jose M.;D'Croz, Luis;Fabeo, Oscar;Ruiz-Perez, Catalina;Darias, Jose;Cueto, Mercedes

DOI: https://doi.org/10.1002/ejoc.200801006

Date: 2009

Abstract:

Gomerolactones A D along with the known majusculone, obtusol, and elatol were isolated from Laurencia majuscula, and their structures were determined spectroscopically. With the aid of Pirkle s reagent at low temperature, NMR spectroscopy was used to determine the absolute configuration at the ring closure carbon atom of a a-alkylidene-?-lactone and an a-alkylidene-d-lactone unit embedded in the chamigrene network of compounds 1 and 2, respectively. The absolute stereochemistry of compounds 3 and 4 was determined by Xray analysis.

Citation:

Diaz Marrero, Ara R., Brito, Inmaculada, de la Rosa, Jose M., D'Croz, Luis, Fabeo, Oscar, Ruiz-Perez, Catalina, Darias, Jose, and Cueto, Mercedes. 2009. "Novel lactone chamigrene-derived metabolites from Laurencia majuscula." European Journal of Organic Chemistry. 2009 (9):1407–1411. https://doi.org/10.1002/ejoc.200801006

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